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Post Doc

 
Requistion ID:  156
Location: 

Copenhagen, N/A, DK

Date:  Feb 04, 2019
 

Post Doc position in Department of Biotherapeutic Discovery

  

We are looking for a highly motivated post doc with a strong interest in neuroimmunology to join our team of scientist in the discovery of novel antibody-based therapies for treating neurodegenerative diseases. The department of Biotherapeutic Discovery is driving research activities for identification of antibody drug candidates to support Lundbeck’s R&D projects. In collaboration with the department of Neuroscience we are expanding our efforts in understanding the therapeutic potential of neuroinflammation for treatment of neurodegenerative diseases. Key activities are focused on evaluating the effects of modulating microglia/macrophage function as a therapeutic approach. Biotherapeutic Discovery is based at Lundbeck’s R&D headquarter in Valby, Copenhagen.

 

Your job and key responsibilities

The job is an experimental scientist position with hands-on laboratory work focusing on evaluation of novel neuroinflammatory targets. You will work in close collaboration with scientists and technicians from different departments. Responsibilities will include establishment and characterization of relevant cellular model systems, in vivo models, in vitro phagocytosis/functional assays and monocyte/macrophage polarization to address key questions on understanding the role of innate immune receptor genes in neurodegeneration.

 

Importantly, the individual will play a key role in experimental activities to support Lundbeck being an EFPIA partner in the IMI2 Consortium PHAGO supported by EU’s research and innovation program, Horizon 2020. This innovative research project is devoted to the development of immunomodulatory therapies for Alzheimer’s disease and brings together international experts on microglial activation/phagocytosis in Alzheimer’s disease pathology. In addition, the successful candidate will be able to independently plan experiments, participate in scientific discussions and present data at scientific meetings.

 

This is an excellent opportunity for a creative scientist who is interested in contributing to industry drug discovery programs targeting neuroinflammation and neurodegeneration.

 

We offer

The opportunity to join a team of highly qualified colleagues working in a scientific environment dedicated to neuroscience in an open international atmosphere with excellent possibilities for skills and scientific expertise development. You will be part of a global and specialized pharmaceutical company with approximately 5,000 employees focused on helping patients with psychiatric and neurological disorders.

 

Qualifications

Our preferred candidate has the following professional and personal qualifications:

·         PhD degree in neuroimmunology, immunology, cell biology or related area

·         Experience with:

o   iPS and/or primary human immune cell cultures

o   Primary mouse microglia cell cultures

o   Functional cellular assays (phagocytosis of various targets, redox state, proteolytic capacity or similar)

o   In vitro polarization of macrophages

o   Analysis of sequencing/transcriptome data

o   Live cell confocal imaging

o   Multi-colour flow cytometry-based bioassays

·         A strong interest in neuroimmunology research.

·         Experience with drug discovery is an advantage.

·         Genuine interest in execution of experimental work and seek to meet high scientific standards.

·         Efficient, goal oriented and independent work style with flexible mind-set.

·         Team player with strong collaboration and communication skills.

·         Fluent in oral and written English.

 

Further information

Please contact Sandra B. Vergo; SBVE@Lundbeck.com +45 30832746. Your application and CV should not be sent via email. We also recommend that you have a look at our website.

 

Your application

Please click on the link below to apply for the job. Applications must be received no later than 24th February 2019.

 

 

 

 

 

 

 

 

Lundbeck is a global pharmaceutical company specialized in brain diseases. For more than 70 years, we have been at the forefront of neuroscience research. We are tirelessly dedicated to restoring brain health, so every person can be their best.


An estimated 700 million people worldwide are living with brain diseases and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with brain diseases – we call this Progress in Mind.

Read more at www.lundbeck.com/global/about-us/progress-in-mind.
Our approximately 5,000 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing and sales. Our pipeline consists of several late-stage development programs and our products are available in more than 100 countries. Our research center is based in Denmark and our production facilities are located in Denmark, France and Italy. Lundbeck generated revenue of DKK 18.1 billion in 2018 (EUR 2.4 billion; USD 2.8 billion).

For additional information, we encourage you to visit our corporate site www.lundbeck.com and connect with us on Twitter at @Lundbeck and via LinkedIn.