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Scientist Computational Chemistry

 
Requistion ID:  1880
Location: 

Copenhagen, Hovedstaden, DK

Date:  03-May-2021
 

Scientist Computational Chemistry

 

Description

Lundbeck is a global pharmaceutical company with approximately 5,000 employees across 55 countries specialized in psychiatric and neurological disorders. At Lundbeck we are highly committed to improving the quality of life of people living with brain disease. The Computational Chemistry department is part of the Division of Molecular Discovery and Innovation within Lundbeck Research. The department currently consists of 5 scientists and is based at Lundbeck’s headquarters in Valby, Copenhagen.

 

The Computational Chemistry department is responsible for all Computational Chemistry/Computer-Assisted Drug Design (CADD), and Structural Biology efforts in Lundbeck Research. We are fully integrated into the discovery process, working with scientists from multiple disciplines from the earliest stage of target validation through hit/lead identification to optimization of compounds for clinical development. Some of our key responsibilities are to support the chemistry and biologics programs with structural understanding, idea generation, and predictive modelling using rational design. The group is continuously looking into new technologies to strengthen our support to medicinal chemistry, e.g. AI, free-energy calculations, and CryoEM. We work closely together in an informal team atmosphere. We are now looking for a new team member.

 

Your job and key responsibilities

Your main responsibilities will be to provide Computational Chemistry input into the drug discovery programs. To impact the success of these you will be directly involved in the drug discovery project teams, where you will proactively use cutting-edge Computational Chemistry and other in silico and data mining approaches. You will use both ligand- and structure-based methods to prioritize and design compound ideas. You will also be responsible for effective delivery of tasks to foster project progression, and lead or contribute to other initiatives to enhance Lundbeck’s drug discovery efforts. You will be working as a keen team player, with the ability to operate independently in an effective, and highly communicative way.

 

We offer

the opportunity to join a team of highly qualified colleagues, where you will have excellent possibilities for scientific and personal development.

 

Qualifications

You are an enthusiastic and motivated scientist with comprehensive experience in Computational Chemistry/Computer-Aided Drug Design (CADD), with the following profile:

  • PhD in a relevant subject with 2-3 years of post PhD experience, preferably in a pharmaceutical company
  • thorough knowledge and experience in structure- and ligand-based drug design, SAR analysis, chemistry, and how structural changes will affect ligand binding as well as druggability.
  • skills in the field of informatics and data analytics
  • enjoy and are effective at being a team player, including 2-way communication, with a can-do attitude.
  • skilled at working with medicinal chemists in hypothesis generation.
  • fluent in written and oral English.

 

Further information

For further information, please contact Head of Computational Chemistry Section, Henrik Keränen on HKER@lundbeck.com.

Your application and CV should not be sent via email.

We also recommend that you have a look at our website.

 

Your application

Applications must be received no later than June 7th, 2021 and should include a cover letter with curriculum vitae as well as the names and contact details for two referees. We will conduct interviews as we receive applications.

Lundbeck is a global pharmaceutical company specialized in brain diseases. For more than 70 years, we have been at the forefront of neuroscience research. We are tirelessly dedicated to restoring brain health, so every person can be their best.
 
Millions of people worldwide live with brain diseases, and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement, and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with brain diseases – we call this Progress in Mind.
 
Read more at www.lundbeck.com/global/about-us/progress-in-mind
 
Our approximately 5,800 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing, and sales. Our pipeline consists of several R&D programs, and our products are available in more than 100 countries. We have research centers in Denmark and the US, and our production facilities are located in Denmark, France, and Italy. Lundbeck generated revenue of DKK 17 billion in 2019 (EUR 2.3 billion; USD 2.6 billion).

For additional information, we encourage you to visit our corporate site www.lundbeck.com, and connect with us on Twitter at @Lundbeck and via LinkedIn.